THE EFFECT OF AEROBIC EXERCISE ON EXPRESSIVE LEVEL OF VCAM-1 AT APOE-DEFICIENT MOUSE AORTA
Journal: Asian Pacific Journal of Microbiology Research (AJMR)
Author: Sunyan, Hao Xuan-ming, Geng Qing-qing, Li Jin-huan, Zhang Yan-yan, Ren qi
This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited
ApoE-deficient mice was used as AS model to approach the effect of aerobic exercise on the expressive level of VCAM-1 on apoE-deficient mouse aorta. METHODS: 20 apoE-deficient mice were randomly divided into control group (CG) and exercise group (EG, swimming, 90min/d, 6d/w, 10 wks)， the expressive level of VCAM-1 on aorta were tested after 10 weeks by immunohistochemistry. RESULTS: Compared with CG, the expressive level of VCAM-1 on the aorta of EG were significantly lower（P<0.01). Conclusion: This result suggested that aerobic exercise improved the local inflammation in apoE-deficient mouse aorta.